SICO-KG-002 · EVIDENCE-LINKED KNOWLEDGE GAIN
Did a candidate gain become part of a continuing research road?
The 24-paper pilot is now linked to later CIDM publications sharing at least two structured dimensions. This tests continuity, not causal influence.
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Strong continuity1
Moderate continuity0
Weak continuity0
No later signalBoundary: a later paper on the same pathogen/technology/theme does not prove the earlier publication caused it. The correct claim is “continuity signal in the CIDM corpus,” not “impact caused by Paper X.”
Strongest downstream continuity signals
| Year | Pilot publication | Later related papers | Years represented | Signal | Example follow-ups |
|---|---|---|---|---|---|
| 2006 | Use of PCR and reverse line blot hybridization macroarray based on 16S-23S rRNA gene internal transcribed spacer sequences for rapid identification of 34 mycobacterium species. | 373 | 20 | STRONG | CPD-0407; CPD-0418; CPD-0429; CPD-0434; CPD-0445 |
| 1997 | Comparison of use of phenotypic and genotypic characteristics for identification of species of the anamorph genus Candida and related teleomorph yeast species. | 318 | 29 | STRONG | CPD-0100; CPD-0102; CPD-0108; CPD-0112; CPD-0114 |
| 2007 | Comparison of single- and multilocus sequence typing and toxin gene profiling for characterization of methicillin-resistant Staphylococcus aureus. | 304 | 19 | STRONG | CPD-0491; CPD-0496; CPD-0499; CPD-0510; CPD-0513 |
| 2006 | Simultaneous detection and identification of Candida, Aspergillus, and Cryptococcus species by reverse line blot hybridization. | 298 | 20 | STRONG | CPD-0418; CPD-0427; CPD-0429; CPD-0433; CPD-0435 |
| 2017 | Shigella species epidemiology and antimicrobial susceptibility: the implications of emerging azithromycin resistance for guiding treatment, guidelines and breakpoints. | 259 | 9 | STRONG | CPD-1290; CPD-1293; CPD-1295; CPD-1296; CPD-1297 |
| 1996 | Sporadic invasion of cultured epithelial cells by Haemophilus influenzae type b. | 256 | 29 | STRONG | CPD-0062; CPD-0065; CPD-0070; CPD-0082; CPD-0094 |
| 1996 | Identification by random amplification of polymorphic DNA of a common molecular type of Cryptococcus neoformans var. neoformans in patients with AIDS or other immunosuppressive conditions. | 249 | 29 | STRONG | CPD-0055; CPD-0056; CPD-0057; CPD-0070; CPD-0071 |
| 2018 | First documented gymnasium cluster of COVID-19 with whole genome sequencing in Australia. | 208 | 8 | STRONG | CPD-1396; CPD-1400; CPD-1403; CPD-1417; CPD-1422 |
| 2008 | Barmah Forest virus serology; implications for diagnosis and public health action. | 201 | 18 | STRONG | CPD-0537; CPD-0539; CPD-0540; CPD-0547; CPD-0550 |
| 1998 | Evaluation of four methods for rapid identification of Staphylococcus aureus from blood cultures. | 190 | 28 | STRONG | CPD-0108; CPD-0112; CPD-0114; CPD-0122; CPD-0124 |
| 2005 | Diagnosis of cerebral cryptococcoma using a computerized analysis of 1H NMR spectra in an animal model. | 177 | 21 | STRONG | CPD-0350; CPD-0352; CPD-0358; CPD-0363; CPD-0370 |
| 2016 | Stimulation with lysates of Aspergillus terreus, Candida krusei and Rhizopus oryzae maximizes cross-reactivity of anti-fungal T cells. | 169 | 10 | STRONG | CPD-1215; CPD-1216; CPD-1217; CPD-1221; CPD-1222 |
Why this matters
We can now begin to distinguish a one-off publication from a paper that sits inside a durable institutional research road. The next step is to combine this with evidence review to ask whether the road reflects validation, boundary expansion, new capability, or merely repeated classification.
Full evidence-link table → · Knowledge Gain Pilot → · Knowledge Journeys →