[
{
"id": "GERG-CIDM-001",
"source_question_id": "UQG-006",
"question": "Why is the Influenza / respiratory viruses × Whole-genome sequencing relationship sparse in the publication corpus, and is this a true capability gap, a terminology/classification gap, or simply an unrepresented relationship?",
"global_status": "SUBSTANTIALLY_RESOLVED_GLOBALLY",
"resolution": "Influenza whole-genome/genomic sequencing is an established global surveillance capability; the remaining iCIDM issue is representation/capability-history calibration rather than whether the relationship exists scientifically.",
"next_state": "U1_REPRESENTATION_UNKNOWN",
"next_action": "Return to classification/detector calibration; reformulate as CIDM adoption/capability-history question if useful.",
"public_sources": [
{
"label": "CDC influenza genetic characterization",
"url": "https://www.cdc.gov/flu/php/viruses/genetic-characterization.html"
},
{
"label": "WHO/GISRS genomics context",
"url": "https://www.who.int/initiatives/global-influenza-surveillance-and-response-system"
}
]
},
{
"id": "GERG-CIDM-002",
"source_question_id": "UQG-008",
"question": "Why is the Influenza / respiratory viruses × Bioinformatics / modelling relationship sparse in the publication corpus, and is this a true capability gap, a terminology/classification gap, or simply an unrepresented relationship?",
"global_status": "SUBSTANTIALLY_RESOLVED_GLOBALLY",
"resolution": "Bioinformatics and modelling are long-established components of influenza surveillance, evolution analysis and vaccine-strain work. The stronger remaining question is how CIDM's documented capability compares with global practice.",
"next_state": "U1_U4_REFORMULATE",
"next_action": "Reformulate from existence question to comparative institutional capability/adoption question.",
"public_sources": [
{
"label": "PubMed: bioinformatics/computational biology in influenza",
"url": "https://pubmed.ncbi.nlm.nih.gov/12686090/"
},
{
"label": "WHO GISRS bioinformatics workshop",
"url": "https://www.who.int/news-room/events/detail/2024/09/27/default-calendar/who-bioinformatics-workshop-to-strengthen-the-global-influenza-surveillance-and-response-system-%28gisrs%29-in-collaboration-with-gisaid-and-who-collaborating-centre-for-influenza-in-australia"
}
]
},
{
"id": "GERG-CIDM-003",
"source_question_id": "UQG-009",
"question": "The Streptococcus pneumoniae × PCR / molecular diagnostics relationship was recurrent but has not appeared recently in the corpus. Is the capability obsolete, absorbed into newer methods, dormant, or simply relabelled?",
"global_status": "SUBSTANTIALLY_RESOLVED_GLOBALLY",
"resolution": "PCR-based pneumococcal detection/serotyping is an established global diagnostic/surveillance capability. The iCIDM question should focus on local historical continuity, relabelling, replacement or documentation rather than whether the method is scientifically established.",
"next_state": "U1_U4_REFORMULATE",
"next_action": "Trace CIDM historical method labels and later replacement technologies; do not promote original existence-gap question.",
"public_sources": [
{
"label": "CDC pneumococcal PCR and serotyping",
"url": "https://www.cdc.gov/strep-lab/php/pneumococcus/serotyping-using-pcr.html"
},
{
"label": "PubMed pneumococcal PCR clinical study",
"url": "https://pubmed.ncbi.nlm.nih.gov/10639531/"
}
]
}
]